mRNA Production CDMOs

Agilent Advanced Therapeutics

United States

BioVectra is a Canadian full-service CDMO specializing in biologics, small molecules, nucleic acids, and fill/finish, now a part of Agilent Technologies. With over 50 years of pharmaceutical manufacturing experience, the company leverages microbial fermentation expertise and complex chemistry to support partners from clinical to commercial stage. BioVectra operates multiple manufacturing facilities in Canada and recently opened a 36,000 sq ft mRNA facility as part of a $90M expansion in Charlottetown.

AsymBio (Asymchem Group)

China

AsymBio, a strategic business unit of Asymchem Group (stock code: 002821.SZ / 6821.HK), is a biologics CDMO focused on antibodies, recombinant proteins, bioconjugates (including ADCs), and mRNA. They provide end-to-end services from cell line construction through commercial manufacturing, with a 130,000+ sq meter Shanghai Fengxian facility featuring 200L/500L/2000L single-use bioreactors. They have supported FDA IND approvals for partners including Radiopharm Theranostics.

BioGeneric Pharma (BGP)

Egypt

BioGeneric Pharma S.A.E (BGP) is an Egyptian international biopharmaceutical company specializing in the development, production, analysis, and marketing of therapeutic recombinant proteins, biosimilars, and vaccines. BGP operates a state-of-the-art biomanufacturing facility in 10th of Ramadan Industrial City, Egypt. The company offers contract manufacturing (CMO) and toll manufacturing services with capabilities spanning biomanufacturing, fill/finish (vials, PFS, cartridges), quality control labs, and mRNA technology (WHO mRNA technology transfer hub partner). Has single-use technology for upstream (25L to 2,000L bioreactors) and downstream processing.

Biomay AG

Austria

Biomay AG is a fully integrated Austrian CDMO founded in 1984, specializing in GMP manufacturing of plasmid DNA (pDNA), messenger RNA (mRNA), and recombinant proteins. They operate two manufacturing sites in Vienna (Seestadt and mRNA Competence Center), offering end-to-end services from gene sequence to large-scale product supply. Biomay has manufactured 200+ GMP plasmid batches and offers personalized patient-specific batches. Member of the Alliance for mRNA Medicines (AMM). Expanding capacity tenfold with new production facility.

BioNTech

Germany

BioNTech SE is a global biotechnology company headquartered in Mainz, Germany, that develops and manufactures mRNA-based immunotherapies and vaccines. While primarily a pharmaceutical innovator, BioNTech operates extensive in-house GMP manufacturing capabilities for mRNA, antibodies, and cell therapies across multiple global sites. They pioneered the BioNTainer modular mRNA manufacturing solution. FDA-registered for API manufacture and analysis. Active in 10+ clinical trials across oncology and infectious disease.

BMI Korea

South Korea

BMI Korea is a South Korean CDMO offering contract development and manufacturing services spanning small molecule APIs, oral solid dosage forms, biologics, vaccines, and mRNA products. The company provides integrated services from formulation development through commercial-scale manufacturing with cGMP-compliant facilities.

Boston Institute of Biotechnology (BIB)

United States

Boston Institute of Biotechnology (BIB) is a US-based full-service CDMO offering cGMP and non-GMP mammalian, microbial, gene therapy, and cell therapy services. The company features the world's first ultra-large bioreactor with 30,000L working volume capacity and provides end-to-end services from cell line development through commercial-scale cGMP manufacturing.

Catalent Pharma Solution

Argentina

Catalent is a leading global CDMO trusted by pharma, biotech, and self-care companies to accelerate the development, manufacturing, and delivery of products that improve lives. With a worldwide network of facilities, advanced technologies, and deep expertise, Catalent provides integrated end-to-end solutions spanning oral dose, biologics, specialty therapies, cell and gene therapy, and clinical supply. The company partners with innovators from early-stage design through commercial manufacturing.

Hanmi Pharm. Co. Ltd

South Korea

Hanmi Pharmaceutical is a major South Korean pharmaceutical company providing comprehensive CDMO services across the entire pharmaceutical lifecycle. The company operates through Paltan Smart Plant (producing 6+ billion chemical drug tablets annually), Pyeongtaek Bioplant (FDA-approved biopharmaceutical manufacturing with 12,500L bioreactors), and Hanmi Fine Chemical (API and raw materials including mRNA cap analogs, NTP, and lipids). Hanmi has partnerships with global pharma companies including Lilly, Roche, and Sanofi.

Lonza

Switzerland

Lonza is a pioneer and world leader in the CDMO industry, founded in Switzerland in 1897. The company provides integrated development and manufacturing services across biologics, small molecules, cell and gene therapy, mRNA, and bioconjugates (ADCs/HPAPIs). With over 20,000 employees across five continents, Lonza serves the global pharmaceutical, biotech, and nutrition industries with end-to-end capabilities from early development to commercial-scale manufacturing.

Novartis Contract Manufacturing

Austria

Novartis Contract Manufacturing is the CDMO arm of Novartis, offering fully integrated end-to-end manufacturing solutions across biologics (mammalian up to 15,000L, microbial up to 13,000L), small molecules (API to fill & finish), cell & gene therapy (CAR-T, AAV, LV), xRNA/LNP/pDNA, and comprehensive fill & finish services. The operation spans multiple state-of-the-art facilities across Austria, Switzerland, Slovenia, Belgium, France, Singapore, and the United States, with 107 FDA inspections and 27 FEI registrations.

Pace® Life Sciences

United States

DUPLICATE ENTRY -- This is the same company as 'Pace Analytical Services LLC (Pace Life Sciences)' (company index 10). Pace Life Sciences is the CDMO/CRO division of Pace Analytical. Same website content, same capabilities. See company index 10 for full profile.

Porton Advanced Solutions

China

Porton Advanced Solutions is a China-based CRO and CDMO specializing in Advanced Therapy Medicinal Products (ATMPs). They provide end-to-end services from cell banking, process and analytical method development, GMP production, to fill and finish. Their platforms include lentivirus (for CAR-T, TCR-T, CAR-NK), plasmid DNA (supercoiled, linear, LcDNA), mRNA and LNP encapsulation, AAV, and bacterial vectors. They have achieved 18 IND approvals across NMPA (13), FDA (4), and MedSafe (1), with 300+ GMP batches and 200+ GMP IITs batches produced.

SyVento BioTech

Poland

SyVento BioTech is a Polish biotechnology CDMO specializing in lipid-based nanocarrier formulations and LNP (lipid nanoparticle) technology for mRNA-based drug products. They offer comprehensive CDMO services for pharma and biotech innovators, covering mRNA synthesis and LNP encapsulation. The company opened a new mRNA manufacturing facility (FlexFactory by Cytiva) spanning over 7,000 m2 including lab and production areas. They have partnerships with Cytiva and signed a Letter of Intent with Mabion S.A. for biologics manufacturing collaboration.

Wacker Biotech

Germany

Wacker Biotech is the CDMO division of Wacker Chemie AG, specializing in advanced biologics manufacturing including proteins, plasmid DNA, mRNA, LNP formulations, live microbial products, and vaccines. With over 30 years of experience and five GMP-compliant facilities in Germany, the Netherlands, and the United States, Wacker Biotech offers process development through commercial-scale manufacturing with E. coli-based technology platforms.

WuXi Biologics

China

WuXi Biologics is a leading global Contract Research, Development, and Manufacturing Organization (CRDMO) for biologics, with over 12,000 employees across the US, Ireland, Germany, China, and Singapore. The company provides end-to-end solutions from discovery through commercial manufacturing for biologics including monoclonal antibodies, bispecifics, ADCs, vaccines, and mRNA products using both mammalian and microbial expression systems.

ACON Pharmaceuticals

United States

ACON Pharmaceuticals Inc is a specialty contract research organization (CRO) based in Cranbury, New Jersey, focused on drug product development. They specialize in drug delivery systems including siRNA, mRNA, liposomes, nanocrystals, and complex generics development via the 505(b)(2) pathway. They are primarily a development-focused CRO, not a manufacturing organization.

Aldevron

United States

Aldevron is a US-based CDMO specializing in manufacturing plasmid DNA, mRNA, and related products for gene therapy, cell therapy, gene editing, and RNA vaccines/therapeutics. The company offers custom and catalog products from research grade through cGMP, with capabilities including mRNA production with LNP encapsulation and fill/finish, supporting discovery through commercialization.

Anemocyte S.r.l.

Italy

Anemocyte is an Italian biotech manufacturing organization (self-described as a BMO) specializing in plasmid DNA, mRNA, and viral vector development and manufacturing for the cell and gene therapy sector. They provide GMP-grade contract manufacturing services for advanced therapies.

BioCina

Australia

BioCina is a global end-to-end biologics CDMO and the only biologics CDMO in Australia approved by the US FDA. Following the merger with NovaCina, the company provides comprehensive biologics CDMO services spanning cell line development, process development, analytical development, GMP manufacturing of biologics drug substance and drug product, and mRNA manufacturing. Operates facilities in Adelaide, Australia with GMP manufacturing capacity up to 1,000L bioreactors.

CATUG (CATUG Biotech)

China

CATUG Biotech (also known as CATUG Biotechnology) is a Chinese CRDMO specializing in plasmid DNA, mRNA, and delivery system manufacturing for cell and gene therapy and nucleic acid therapeutics. The company operates a one-stop service platform covering plasmid CDMO, mRNA CDMO, and delivery system CDMO services, including GMP manufacturing, sterile filling, and analytical/quality study services. CATUG provides end-to-end support from research customization through CMC to technology transfer and GMP production.

Center for Breakthrough Medicines (CBM)

United States

Center for Breakthrough Medicines (CBM) is a cell and gene therapy CDMO based in King of Prussia, Pennsylvania, operating at The Discovery Labs campus. CBM offers comprehensive services including plasmid manufacturing (Precision Plasmids), viral vector manufacturing (Genesis Vector Manufacturing Solutions), cell therapy manufacturing, and analytical testing (Analytical Accelerator for AAV testing). SK Pharmteco acquired controlling interest in CBM, and the company has capacity to manufacture therapies for 10,000+ patients.

Certest Pharma

Spain

Certest Pharma is the pharmaceutical division of Certest Biotec S.L., established in Zaragoza, Spain in 2002. The company specializes in advanced lipid nanoparticle (LNP) technology for RNA and oligonucleotide therapeutics delivery, with over 1,500 proprietary ionizable lipids. Certest Pharma has both R&D and GMP manufacturing capabilities for LNP formulations, and has partnerships with CordenPharma and Curapath for LNP delivery systems.

Codexis, Inc.

United States

Codexis, Inc. is a US-based enzyme engineering and biocatalysis company that provides contract manufacturing of RNA therapeutics through its ECO Synthesis Manufacturing Platform, as well as pharmaceutical biocatalysis services for small molecule API manufacturing. The company uses proprietary enzyme-enabled platforms to deliver enzymatic RNA synthesis (siRNA, mRNA) as an alternative to traditional chemical synthesis, offering higher purity, yield, and sustainability.

CoJourney Inc

China

CoJourney Inc is a CDMO partner specializing in cGMP manufacturing for gene therapies, featuring its proprietary Zero Chrom plasmid manufacturing platform that eliminates chromatography for higher purity and lower cost. The company provides plasmid DNA, viral vector (AAV, lentivirus, adenovirus), sgRNA GMP manufacturing, and exosome manufacturing services, having served over 100 customers and delivered more than 400 batches with a proven IND approval track record with FDA and CDE.

Fraunhofer Institute for Cell Therapy and Immunology (IZI)

Germany

The Fraunhofer Institute for Cell Therapy and Immunology (IZI) in Leipzig is a contract research and GMP manufacturing institute specializing in cell and gene therapy, vaccines, and biologics. The institute provides GMP-compliant manufacturing of clinical trial materials (ATMPs and biologicals), process development for pharmaceutical manufacturing, and regulatory support for manufacturing authorizations and approvals.

Helix Biotech, Inc.

United States

Helix Biotech, Inc. is a U.S.-based CDMO specializing in GMP formulation and RNA manufacturing, including DNA, RNA, and LNP (lipid nanoparticle) formulations. The company offers end-to-end services from RNA construct design through its StrandSolve platform to GMP manufacturing via its NOVA IJM nanoparticle formulation platform.

Hongene Biotech

China

Hongene Biotech is a China-based CDMO specializing in oligonucleotide and mRNA manufacturing services. The company provides custom DNA/RNA synthesis and large-scale oligonucleotide production for pharmaceutical and biotech customers globally.

NorthX Biologics

Sweden

NorthX Biologics is a Swedish CDMO specializing in advanced biologics and ATMPs (Advanced Therapy Medicinal Products). The company offers end-to-end services from process development to GMP manufacturing for recombinant proteins, viral vectors, plasmid DNA, cell therapy, extracellular vesicles, and mRNA. Recognized by the Swedish Government as an international competence center and innovation hub in 2021, NorthX has 30+ years of GMP manufacturing experience.

Recipharm AB

Sweden

Rechon Life Science AB is a subsidiary/entity within the Recipharm group, the global CDMO headquartered in Stockholm, Sweden. This entry represents the same Recipharm organization (same website: recipharm.com) with its extensive global manufacturing footprint of 15+ FDA-registered FEI numbers and 52 FDA inspections. The Perplexity research confirms Recipharm's specialization in oral solid dose, inhalation, sterile manufacturing, and HPAPI capabilities. Rechon may represent a specific Recipharm site or legacy entity. Duplicate of Recipharm AB entry -- capabilities are identical.

RiboPro B.V.

Netherlands

RiboPro B.V. is a Netherlands-based mRNA CDMO providing GMP-grade mRNA manufacturing, LNP (lipid nanoparticle) formulation services, and contract research. The company has over a decade of mRNA-specific experience and offers proprietary technologies including RiboStealth sequence optimization and RiboFlux GMP manufacturing platform. RiboPro serves customers ranging from early discovery through commercial production of mRNA therapeutics and vaccines.

Touchlight

United Kingdom

Touchlight is a UK-based CDMO pioneering enzymatic GMP DNA production using its proprietary cell-free dbDNA technology. Founded in 2007 and based in London, the company manufactures high-purity DNA for genetic medicines across applications including mRNA, AAV viral vectors, lentiviral vectors, gene editing, DNA vaccines, and non-viral gene therapy. Touchlight holds a world-first MHRA GMP certification for synthetic DNA manufacturing and has 9 programs in the clinic using dbDNA.

Creative Biogene

United States

Creative Biogene is a US-based biotech CDMO offering microbial production services for drug substances, GMP-grade mRNA production, and cGMP cell line development. The company provides end-to-end services from oligonucleotide R&D to drug product manufacturing, with capabilities spanning bacterial and yeast-based production systems.

ElevateBio (BaseCamp)

United States

ElevateBio is a US-based genetic medicines company whose BaseCamp division operates as a cGMP manufacturing CDMO for cell therapy, gene therapy, and mRNA products. BaseCamp provides development and manufacturing services from concept through commercialization, leveraging state-of-the-art facilities and proprietary technologies. The company has achieved six consecutive years of revenue growth and holds ICMC certification for its manufacturing operations.

Euticals (now part of Curia)

France

Euticals, now part of Curia Global, is a global CDMO with over 30 years of experience in drug discovery, development, and manufacturing across small molecules, generic APIs, sterile drug products, and biologics. Curia (which acquired Euticals through AMRI) operates an extensive global network with hundreds of FDA-registered facilities and provides end-to-end services from API manufacturing through sterile fill/finish.

Evonik Industries AG

Canada

Evonik Industries AG is a global specialty chemicals company that operates as a leading CDMO for complex parenteral drug products, focusing on polymeric and lipid-based delivery systems including liposomes, nanoparticles, microparticles, implants, and LNP formulations. The company's Health Care division provides end-to-end CDMO services for small molecules, peptides, nucleic acids (mRNA, siRNA), and HPAPIs, with FDA-inspected facilities in the US and Canada and 34 FDA inspections with zero OAI outcomes.

eXmoor Pharma Concepts Ltd

United Kingdom

eXmoor Pharma is a UK-based integrated cell and gene therapy CDMO with over 20 years of consultancy expertise embedded across CMC development, process development, GMP manufacturing, and commercialization. The company operates a 65,000 sq ft facility near Bristol with four Grade C process-agnostic GMP clean rooms, supporting viral vectors, autologous and allogeneic cell therapies, and RNA technologies.

Flash BioSolutions

France

Flash BioSolutions (also branded as RNAlead) is a French CDMO specializing in the industrial-scale production of DNA and RNA vectors for gene therapy, cell therapy, vaccination, and genome editing applications. Its proprietary FlashRNA technology combines lentiviral cell transfer functions with bacteriophage RNA packaging for multi-RNA delivery, with GMP production initiated for next-generation mRNA vaccines and therapies.

GC Biopharma

South Korea

GC Biopharma is a South Korean biopharmaceutical company specializing in vaccines, plasma-derived therapies, and biologics. The company provides Vial and Pre-Filled Syringe (PFS) Fill & Finish CMO services and drug product (DP) manufacturing as CDMO services. GC Biopharma has established an mRNA production facility at its Hwasun plant and operates multiple manufacturing sites including Ochang, Hwasun, and Eumseong plants.

Guangzhou Packgene Biotechnology Co Ltd (PackGene)

China

PackGene Biotech is a Chinese cell and gene therapy CRO and CDMO providing comprehensive AAV, lentivirus, mRNA, and plasmid services from discovery through GMP manufacturing. The company operates a 120,000 sq ft GMP facility for viral vector production and has served over 1,000 clients globally with more than 50,000 projects delivered.

Leanbio

Spain

Leanbio is a Spanish biopharmaceutical CDMO founded in 2014 by Dr. Andreu Soldevila and Albert Font, specializing in end-to-end development and manufacturing of biological products including recombinant proteins, antibodies, bioconjugates, and mRNA. Offers both microbial and mammalian production platforms. Acquired by Reig Jofre to strengthen their CDMO capabilities. Currently building a new GMP biologics facility in Sant Quirze del Valles, Barcelona, with an additional 20M EUR investment, featuring over 4,000 sqm and three manufacturing areas: one each for microbial, mammalian, and mRNA production.

Pace Life Sciences is a division of Pace Analytical Services LLC, operating as a full-service CDMO/CRO network across the United States. The company supports drug development across the entire lifecycle from preclinical research through commercialization, specializing in small molecules, biologics (proteins, peptides, monoclonal antibodies, ADCs), nucleic acids (oligonucleotides, mRNA, plasmid DNA), and gene therapies. Recognized by PharmaSource as a Top CDMO in the United States. Operates 9+ strategically located sites including a sterile fill-finish Center of Excellence in Salem, NH.

ST Pharm is a South Korean global API CDMO company founded in 1983, specializing in small molecule APIs, oligonucleotide therapeutics (ASO, siRNA, aptamers), and mRNA-LNP manufacturing. The company operates cGMP manufacturing facilities in South Korea and has a CRO subsidiary (AnaPath) in Switzerland and Spain for preclinical pathology services.

TriLink BioTechnologies LLC

United States

TriLink BioTechnologies LLC is a US-based CDMO (part of Maravai LifeSciences) specializing in nucleic acid chemistry and mRNA production. They offer CleanCap capping technology, custom mRNA synthesis and manufacturing (research through GMP clinical and commercial), custom oligonucleotide synthesis, guide RNA (gRNA) for CRISPR, and NTP (nucleotide) manufacturing. Their 118,000 sq ft facility contains multiple specialized GMP manufacturing suites. Over 110 GMP mRNA batches manufactured and 500+ CleanCap mRNA constructs enabled for preclinical/clinical programs.

Vibalogics is a specialized global CDMO for virotherapy manufacturing, now operating as Recipharm Advanced Bio after acquisition by Recipharm AB. The company offers process and analytical development, GMP manufacturing of viral vectors, oncolytic viruses, and advanced therapies. Capabilities include xRNA therapies, viral vectors (AAV, lentivirus), microbial/live biotherapeutic products, recombinant proteins, plasmid DNA, and lipid nanoparticles. Major $50M expansion of Cuxhaven facility (500L manufacturing line) completed. 118,000 sq ft GMP facility in Massachusetts (US) also completed.

etherna (including its manufacturing arm etherna manufacturing) is a Belgian mRNA technology platform company that designs and manufactures research-grade and GMP-grade mRNA. The company provides custom drug delivery and mRNA manufacturing services, supporting partners from concept through clinical development.

Exothera S.A. is a Belgian CDMO specialized in the development and manufacture of viral vectors for vaccines and gene therapies, as well as RNA therapeutics. The company received GMP certification for its facilities in Jumet, Belgium, and has launched its mRNA Ntensify platform while establishing a facility in Massachusetts to expand its North American footprint.

Life Edit Therapeutics

United States

Life Edit Therapeutics is a gene editing R&D company and business unit of ElevateBio, focused on discovering and developing novel gene editing tools and technologies. The company collaborates with pharmaceutical companies like Novo Nordisk and Moderna on gene editing research. Life Edit is not a contract manufacturer; it is an internal R&D platform within ElevateBio.