Dosage Form
Oral Solid Dose CDMOs
Compare CDMOs manufacturing oral solid dosage forms -- tablets, capsules, and modified-release products. Filter by batch size, coating technology, and regulatory approvals.
373 companies listed
About Oral Solid Dose Manufacturing
Oral solid dose (OSD) is the most common pharmaceutical dosage form, accounting for approximately 60% of all drug products. Manufacturing involves blending, granulation (wet or dry), compression or encapsulation, film coating, and packaging. CDMOs range from small clinical-batch operations to high-throughput commercial manufacturers producing millions of units daily.
Modified-release technologies differentiate advanced OSD CDMOs. Extended-release, delayed-release, and pulsatile-release formulations improve patient compliance and can extend product lifecycle. Technologies include matrix tablets, osmotic systems, multiparticulate systems (coated pellets in capsules), and multi-layer tablets for combination products.
Scale is a key selection criterion. Clinical-phase OSD often runs in batches of 5,000-50,000 units. Commercial scale may mean 500,000+ units per batch. Equipment compatibility (granulators, presses, coaters) must match your projected volumes. Ask about batch success rates and changeover times between products.
Companies (373)
Confab Laboratories
Canada
Confab Laboratories is a well-established CDMO located on Montreal's South Shore, Canada, specializing in non-sterile pharmaceutical manufacturing of liquid, solid, and semi-solid dosage forms. The company provides end-to-end services including formulation development, technology transfer, analytical services, and commercial manufacturing for prescription, OTC, generic, controlled drugs, and veterinary products. Confab operates a 100,200 square-foot GMP facility with 32 manufacturing suites and 17 packaging suites, approved by both the FDA and Health Canada.
Formulation DevelopmentOral Solid DoseSolid Dose Manufacturing
Contract Pharmacal Corp (CPC)
United States
Contract Pharmacal Corp (CPC) is a leading CDMO for the nutraceutical and pharmaceutical industries, headquartered in Hauppauge, New York. The company has over 50 years of experience in developing and manufacturing solid-dose OTC drugs, dietary supplements, and Rx products, with an annual capacity of 25 billion solid doses. CPC manufactures tablets, bilayered tablets, capsules, banded capsules, pellets, granules, powders, and effervescents, and partners with major brands including Tylenol, Centrum, and Breckenridge Pharmaceutical.
Frequently Asked Questions
What types of oral solid dose forms can CDMOs produce?+
Common forms include: immediate-release tablets, film-coated tablets, enteric-coated tablets, extended-release tablets, orally disintegrating tablets (ODTs), hard gelatin capsules, HPMC capsules, softgel capsules, modified-release pellets in capsules, and powder-filled capsules. Specialty forms include multi-layer tablets, osmotic tablets (OROS), and abuse-deterrent formulations.
What is the typical timeline for developing an oral solid dose product?+
From API availability to first clinical batch: 3-6 months for standard formulations, 6-12 months for modified-release. Process development through commercial validation: additional 6-12 months. Total from formulation start to commercial readiness: 12-24 months. Bioavailability-enhancement formulations (amorphous dispersions, nanoparticles) add 3-6 months for technology selection and optimization.
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