Ophthalmology CDMOs

Laboratório Edol, S.A.

Portugal

Laboratorio Edol, S.A. is a Portuguese pharmaceutical company specializing in development, manufacturing, and marketing of medicines, medical devices, cosmetics, and food supplements, with a focus on Ophthalmology, Dermatology, Otorhinolaryngology, and Dermocosmetics. They operate from their factory in Linda-a-Velha, Portugal and offer contract manufacturing (producao para terceiros) services across a wide range of pharmaceutical forms including small and large volume injectables, gels, creams, ointments, syrups, oral solutions and suspensions, cutaneous solutions, and enemas. They have two industrial units equipped for third-party manufacturing.

MAKCUR LABORATORIES LTD.

India

MAKCUR LABORATORIES LTD. is an Indian pharmaceutical manufacturer specializing in small volume parenterals (liquid vials/ampoules), powder injections, and ophthalmic/otic drops. The company manufactures a range of finished dosage forms including antibiotics, anti-inflammatory, antifungal, and ophthalmic preparations. Products include branded formulations in eye/ear drops, liquid injections, and topical preparations. Located in Naroda-Dehgam, Gujarat, India.

MEMPHIS VISION CARE PVT. LTD.

India

Memphis Vision Care Pvt Ltd (MVCPL) is an Indian pharmaceutical company based in Chhatral, Gujarat, that manufactures, supplies, and exports parenteral formulations packed in sterile pre-filled syringes (PFS). Their product segments include ophthalmic care (HPMC ophthalmic solution, sodium hyaluronate, trypan blue), cardiac/critical care (enoxaparin sodium injection, heparin sodium injection), orthopedic (sodium hyaluronate orthopaedic injection), gynecology (iron sucrose injection), and nutritive supplements (phytomenadione injection). The company operates under a hygienic controlled environment with focus on quality commitment and diverse parenteral portfolio.

Midas Pharma GmbH

Germany

Midas Pharma GmbH is a German pharmaceutical company headquartered in Ingelheim, providing end-to-end services across the pharmaceutical value chain including contract development, contract manufacturing, supply chain management, regulatory affairs, quality and compliance, IP services, and reference product sourcing. The company has a particular specialization in Hot Melt Extrusion (HME) technology for high potent drugs with over 10 years of hands-on experience. Midas has FDA and EU GMP-certified manufacturing sites and offers contract manufacturing of finished dosage forms, intermediates, and drug substances. They also have a biosimilar pipeline including Ranibizumab.

Omisan Farmaceutici SRL

Italy

Omisan Farmaceutici SRL is an Italian company specializing in the development, production, and commercialization of sterile medical devices for ophthalmic care. The company offers private label and contract manufacturing (CDMO) services and is the official manufacturer for several leading multinational ophthalmic companies, with products distributed in more than 40 countries.

Oxford Biomedica (OXB)

United Kingdom

Oxford Biomedica (OXB) is a global, quality- and innovation-led CDMO specializing in viral vector development and manufacturing for cell and gene therapy. With 25+ years of experience, OXB is the first and currently only FDA-approved CDMO for commercial production of lentiviral vectors for CAR-T therapy. The company operates GMP suites across three countries with extensive end-to-end capabilities in lentivirus, AAV, and adenovirus vectors.

Steroid S.p.A.

Italy

Steroid S.p.A. is one of the oldest privately-owned steroid API manufacturing companies, founded in the early 1950s in Italy. The company specializes in the synthesis of steroid esters including corticosteroids, progestinics, hormones, anabolics, and estrogens for both human and veterinary use, with over 15 tons installed capacity.

Trifarma S.p.A.

Italy

Trifarma S.p.A. is an international and independent Italian group dedicated to developing, manufacturing, and supplying high-quality Active Pharmaceutical Ingredients (APIs) to the global pharmaceutical industry. The company has R&D laboratories for synthetic organic chemistry process development at lab and pilot scale, with rapid lab-to-industrial scale development. API portfolio covers cardiovascular, anti-infective, nervous system, dermatological/ophthalmic, steroids, and musculoskeletal categories.

UniD Manufacturing

Belgium

UniD Manufacturing is a Belgian CDMO fully dedicated to polymer-based long-acting formulations for sustained release and local delivery of drugs. They offer end-to-end services from proof of concept to commercialization, specializing in non-biodegradable (up to 9 years release), biodegradable (3-18 months), and resorbable (1 day to 3 months) polymer technology platforms. Applications include vaginal rings, ophthalmic implants, inserts, and other implantable dosage forms. They have 20+ years of expertise and GMP-approved cleanrooms accredited for multi-product manufacturing, with required facilities for high-potent APIs (hormones, peptides).

Caplin Point Laboratories is a fully integrated Indian pharmaceutical company with a dominant presence in Latin America and Francophone Africa, and a growing presence in the US and EU. Through its subsidiary Caplin Steriles, the company manufactures sterile injectables, ophthalmic products, pre-mix bags, and pre-filled syringes, with 46 FDA-approved products.

Galentic Pharma (India) Pvt Ltd

India

Galentic Pharma (India) Pvt Ltd is an Indian contract manufacturer established in 1992, specializing in sterile ophthalmic products and non-sterile dermatological products. The company operates two US FDA cGMP compliant and WHO-GMP approved manufacturing facilities with both aseptic and non-sterile capabilities. Galentic exports over 80 products to multiple countries including ophthalmic ointments/gels and a diverse range of derma topicals.

Global Calcium Pvt. Ltd.

India

Global Calcium Pvt. Ltd. is a leading API manufacturer based in Bangalore, India, specializing in specialty APIs including benzodiazepines, ophthalmics, oncology compounds, and chelated mineral salts. The company operates 14 manufacturing plants with over 1,400 employees and exports to 80 countries. Facilities are cGMP, EU GMP, COFEPRIS certified, and WHO cGMP accredited with HACCP and ISO certifications.

Jubilant HollisterStier CMO

Canada

Jubilant HollisterStier CMO (subsidiary of Jubilant Pharma) specializes in sterile fill-finish, lyophilization, injectables, ophthalmics, otics, topicals, and liquids for pharmaceutical and biopharmaceutical clients. End-to-end services from process development to inspection and packaging. Facilities in Spokane, WA and Montreal, QC. Won AWB Manufacturer of the Year 2024 and Manufacturing Excellence Award 2025. Largest manufacturer by employees in Spokane area. 92% repeat customer rate. FDA registered with 4 FEI numbers, 28 inspections (6 NAI, 18 VAI, 4 OAI -- elevated regulatory risk).

Laboratorios Salvat, S.A.

Spain

Laboratorios Salvat is a Spanish pharmaceutical company with over 60 years of experience offering CDMO services. Listed on CPHI Online as a contract development and manufacturing organization, the company is recognized in the ophthalmic drugs contract manufacturing market alongside major players like Lonza and Siegfried. Their Pharmaloop facility enhances production capabilities. Primarily focused on sterile ophthalmic and otolaryngology products.

Murli Krishna Pharma Pvt Ltd

India

Duplicate entry for Murli Krishna Pharma Private Ltd. (mkppl.com) - same company, same website domain. Indian pharmaceutical CDMO specializing in PFI and FDF products with CRAMS services.

Parexel International (MA) Corporation

Argentina

Parexel is a global contract research organization (CRO) providing clinical trial management, regulatory consulting, and biopharmaceutical development services. With over 24,000 professionals and 50+ clinical sites across five continents, the company offers Phase I-IV clinical trial services, CMC regulatory strategy, and real-world evidence generation. Parexel is primarily a CRO, not a drug manufacturer.

Piramal Pharma Solutions (PPS) is a global CDMO under Piramal Pharma Limited, offering end-to-end development and manufacturing solutions across the drug lifecycle. Operates through a globally integrated network of 17 development and manufacturing facilities across North America, Europe, and Asia, with distribution in 100+ countries. Services include drug discovery, process/pharmaceutical development, clinical trial supplies, and commercial supply of APIs and finished dosage forms. Specialized in highly potent APIs, antibody-drug conjugations, sterile fill/finish, and peptide products. Multiple CDMO Leadership Award winner.

US-based topical and transdermal pharmaceutical CDMO, now merged with MedPharm (Durham, NC). Provides end-to-end services from formulation development through commercial manufacturing for topical, transmucosal, and transdermal drug products. Specializes in semi-solids, aerosols, liquids, injections, and transdermal patches. Offers in-vitro permeation testing (IVPT), in-vitro release testing (IVRT), disease activity models, tissue protein binding, and continuous flow technologies. GMP-certified manufacturing for generics, OTC, and prescription products.

Unither Pharmaceuticals is a global CDMO specializing in sterile and non-sterile liquid pharmaceutical forms, and the world leader in Blow-Fill-Seal (BFS) technology with annual production capacity exceeding 5 billion doses. Founded in 1993 in France, they operate 9 production sites across Europe, North America, South America, and China with 2,500+ employees. They offer contract manufacturing (clinical and commercial), formulation/analytical development, out-licensing of turnkey products, co-development partnerships, and regulatory support including CTD/eCTD submissions. Products include BFS single-doses, multi-doses, vials, sprays, stick packs, and ophthalmic solutions.

Cayman Pharma s.r.o. is a Czech pharmaceutical manufacturer specializing in cGMP prostaglandin Active Pharmaceutical Ingredients (APIs) for ophthalmology and vascular applications. The company owns a patented route to the prostaglandin core structure developed at its headquarters near Prague, and produces APIs including Latanoprost, Travoprost, Bimatoprost, Tafluprost, and Epoprostenol. cGMP compliance is continuously verified by Czech NCAs (SUKL, USKVBL) and the US FDA.

Farmigea S.p.A. is an Italian pharmaceutical company based in Pisa, established in 1946, specializing in ophthalmology for nearly 80 years. The company offers CDMO services for development and manufacturing of sterile topical ophthalmic products, with its production plant authorized for all sterile ophthalmic dosage forms.

Genezen Labs (India) is the Indian entity of Genezen, a cell and gene therapy CDMO specializing in viral vector manufacturing services. The company provides lentiviral, retroviral, and adeno-associated viral (AAV) vector CDMO services, along with cell therapy manufacturing and plasmid design. Genezen operates a 60,000 sq ft cGMP facility in Fishers, Indiana and an 86,000 sq ft licensed viral vector manufacturing facility in Lexington, Massachusetts.

MassBiologics, a division of UMass Chan Medical School, is a US-based biologics CDMO with over 100 years of history driving discoveries to products. The organization develops novel biologics for diseases of public health importance and offers CMO services including bulk drug manufacture of monoclonal antibodies, vectored therapeutics (gene therapy), and aseptic fill finish. The facility includes approximately 25,000 sq ft of cGMP manufacturing space with dedicated aseptic fill finish and bulk drug substance areas. FDA-registered with 3 FEI numbers. Produces the FDA-licensed Td vaccine and has partnerships for gene therapy manufacturing (SparingVision, PTC Therapeutics).

Dubourgel Medical is a French company specializing in the design and manufacture of medical devices for various medical procedures including hyaluronic acid injection syringe accessories, blood analysis tools, surgical instruments, and orthopedic devices. The company is not a pharmaceutical drug manufacturer.

EMA Pharmaceuticals (Ema Pharma)

France

EMA Pharmaceuticals (Ema Pharma) is a French manufacturer of overseals (crimping capsules) for injectable pharmaceutical applications. The company specializes in sealing solutions for vials used in pharmaceutical injectable products, manufactured in a GMP-compliant facility. Note: The FDA regulatory data (90 approved products, 184 recalls) appears to be associated with a different entity sharing the FEI registrations, not the French crimp cap manufacturer.

Laboratoires Théa

France

Laboratoires Thea is an independent French pharmaceutical company based in Clermont-Ferrand, 100% dedicated to ophthalmology. They are Europe's leading independent eye-care group, specializing in researching, developing, manufacturing, and commercializing ophthalmic products including preservative-free eye drops and drug delivery systems for glaucoma, dry eye, allergies, infections, inflammation, and retinal disorders. They are present in 70+ countries and have partnerships with companies like LENZ Therapeutics, Novaliq, and ProQR. While they manufacture their own products, they are a branded pharmaceutical company, not a CDMO or contract manufacturer.

Indian pharmaceutical CDMO specializing in pre-finished formulation intermediates (PFI) and finished dosage forms (FDF). Manufactures oral solids, oral liquids, injectables, ophthalmics, topicals, and inhalation products. Strong focus on pellet technology and nanotechnology-based drug delivery systems. CRAMS (Contract Research and Manufacturing Services) provider.

NEON LABORATORIES LTD

India

Indian pharmaceutical company (established 1984) that emerged as a leader in anesthesia and critical care products. Manufactures 500+ products sold in 70+ markets. Multi-located manufacturing facilities including API and formulations. Started as contract manufacturer for anesthesia products (1992) and grew into branded generics. Major plant at Palghar with 460 million units capacity. Has dedicated manufacturing units for cephalosporins and oncology to avoid cross-contamination. 2000+ employees. FDA registered with 3 FEI numbers, 29 inspections (13 NAI, 15 VAI, 1 OAI). Began API production in 2008. Also has medical devices division (HOSPRO).

SteriMax Inc.

Canada

SteriMax Inc. is a family-owned Canadian specialty pharmaceutical company based in Oakville, Ontario. They develop, source, manufacture, market, and distribute essential hospital and retail pharmacy products to the Canadian healthcare market. Their portfolio includes generic and branded products across sterile injectables, oral solids, and other essential products. SteriMax has a Health Canada-approved QC lab and their products are manufactured in Health Canada, FDA, or EMEA approved facilities. While they have some internal pharmaceutical manufacturing capabilities (their website mentions production and manufacturing), their primary model appears to be sourcing, marketing, and distributing pharmaceutical products in Canada rather than offering contract manufacturing services to third parties. They are not positioned as a CDMO/CMO.

Jiangsu Hengrui Medicine Co., Ltd. is China's largest listed pharmaceutical company, founded in 1970, with over 20,000 employees globally. Hengrui is primarily an innovation-driven pharma company developing and manufacturing its own drugs across oncology, cardiovascular, metabolism, autoimmune, pain, and anti-infection therapeutic areas, with a pipeline of 257 drugs and 24 Class 1 innovative drugs. While it has some CDMO references in search results, Perplexity research confirms it primarily specializes in proprietary drug development and manufacturing rather than contract services.

Sun Pharmaceutical Industries Ltd. (Sun Pharma) is one of the world's largest specialty generic pharmaceutical companies, headquartered in Mumbai, India. While the company has massive manufacturing operations (1,075 FDA-approved products, 25+ FDA-registered FEI numbers), it primarily manufactures and markets its own branded and generic pharmaceutical products rather than providing contract manufacturing services to third parties as a CDMO.