Vial Fill-Finish CDMOs

Pyramid Laboratories

United States

Pyramid Laboratories (now Pyramid Pharma Services) is a California-based CDMO established in 1988, specializing in aseptic manufacturing, development, and analytical services for parenteral drugs. The company supports biologics, peptide, and small molecule drugs from pre-clinical development through commercial supply. Pyramid operates a 90,000 sq ft GMP-compliant facility in Costa Mesa, California, and has received investment from Audax Private Equity.

Rentschler Biopharma

Germany

Rentschler Biopharma is a leading global CDMO focused exclusively on biopharmaceuticals, with over 50 years of industry experience. The company contributed to nearly 25% of FDA-approved biopharmaceuticals in 2023, has supported 180+ biotherapeutics, and serves 180+ clients worldwide. It is an independent family-owned company employing approximately 1,400 people.

Sanochemia Pharmazeutika AG

Austria

Sanochemia Pharmazeutika AG is an Austrian pharmaceutical manufacturer specializing in contrast media (MRI and CT), APIs, and finished dosage forms. Located in Neufeld an der Leitha with over 130 years of history, the company produces over 4 million units of sterile injectable contrast media annually and offers CDMO/CMO services for APIs and drug products.

ScinoPharm (scinopharm.com)

China

ScinoPharm Taiwan is a CDMO headquartered in Tainan Science Park, Taiwan, specializing in high-tech oncology APIs, peptide synthesis, and sterile injectable drug products. With FDA-approved facilities and 18 flexible manufacturing lines, ScinoPharm provides end-to-end services from API development through sterile injectable fill/finish, with a strong focus on complex generics and oncology therapeutics.

Serumwerk Bernburg AG

Germany

Serumwerk Bernburg AG is a medium-sized German pharmaceutical company with over 60 years of tradition in the development and production of medicines, medical devices, and APIs. The company offers APIs and contract manufacturing (Lohnproduktion) services, manufactures sterile infusion and rinsing solutions for hospitals and dialysis centers, ophthalmic products, veterinary medicines, wound care products, and specialty biopolymer-based formulations. Serumwerk has FDA-registered API manufacturing and exports to partners in 60+ countries.

Simtra BioPharma Solutions

Germany

Simtra BioPharma Solutions is a global CDMO focused exclusively on sterile injectable drug products. With over 65 years of expertise, Simtra offers formulation development, lyophilization cycle optimization, technology transfer, analytical services, fill/finish operations, specialized containment, and global regulatory support. They handle cytotoxics, highly potent compounds, biologics, vaccines, small molecules, ADCs, and diluents. They have a strategic alliance with MilliporeSigma for ADC manufacturing. The company has transferred 60+ ADC candidates including six commercial products to their German site.

SK bioscience

South Korea

SK bioscience is a South Korean vaccine-focused biopharmaceutical company that also operates as a CDMO. Listed on KOSPI (302440), they develop proprietary vaccines (influenza, varicella, COVID-19, pneumococcal, HPV, RSV) and provide CDMO/CMO services for vaccine manufacturing. They acquired a controlling stake in German CDMO IDT Biologika for approximately $244M, gaining manufacturing sites in Dessau (Germany) and Rockville (Maryland, USA). SK bioscience collaborates with the Bill & Melinda Gates Foundation, CEPI, and international vaccine initiatives. They have WHO prequalified products.

SpectronRx

Belgium

SpectronRx is a radiopharmaceutical CDMO headquartered in Belgium with manufacturing facilities in Indiana, USA, and Danbury, Connecticut. The company specializes in end-to-end radiopharmaceutical and theranostic services including mAb, nanobody, and peptide radiolabeling with a wide range of isotopes (Ac-225, Pb-212, Lu-177, I-123/131, Cu-64/67, etc.), isotope production via cyclotron (16-70 MeV), worldwide cold-chain logistics, and regulatory consulting from IND filing through FDA approval. They operate 3 CDMO facilities with multiple cleanrooms and GMP-aligned space totaling approximately 200,000 sq-ft.

Stira Pharmaceuticals (Sterile Injectable CDMO)

United States

Stira Pharmaceuticals is a U.S.-based CDMO specializing in the development and cGMP manufacture of complex sterile injectable products, with integrated analytical capabilities. Founded in 2019, the company serves the U.S. market with services spanning small molecules, peptides, oligonucleotides, and biosimilars in formats including vials, syringes, IV bags, and cartridges with batch sizes up to 2,000L.

Symbiosis Pharmaceutical Services

United Kingdom

Symbiosis Pharmaceutical Services is a world-class sterile fill-finish CDMO based in Stirling, UK, specializing in the GMP manufacture of liquid and lyophilized biological and small molecule drug products. The company serves clinical trial and commercial scale with FDA-inspected and MHRA-licensed facilities. Symbiosis has manufactured its first 10,000-vial commercial batch for a cancer immunotherapy currently in Phase III trials. The company handles a full range of biologics including ATMPs, viral vectors, mAbs, ADCs, RNA/peptide therapies, and vaccines.

Sypharma Pty Ltd

Australia

Sypharma is an Australian specialty contract manufacturing group operating since 2005. They develop and manufacture therapeutic goods, veterinary products, and specialty consumer products. They specialize in contract manufacturing for early clinical through Phase III clinical trials and have multipurpose cleanrooms for oral, topical, and parenteral drug products. They manufacture both large and small volume parenterals and have a veterinary manufacturing suite. Licensed by FDA, TGA, and ISO 13485 certified. They partnered with Schott on sterile fill/finish capabilities.

Tanvex Biopharma USA, Inc

Taiwan

Tanvex BioPharma USA is a vertically-integrated biopharmaceutical company that has launched a CDMO division (Tanvex CDMO) offering pre-clinical through commercial-scale contract manufacturing of microbial and mammalian-derived biotherapeutics. Founded by Dr. Allen Chao (former founder/CEO of Watson Pharmaceuticals). They received FDA approval for Nypozi (biosimilar filgrastim) and have an FDA-accepted biosimilar BLA. The CDMO offers end-to-end biologics manufacturing services. Their San Diego facility is FDA-registered with 1 approved product (injectable). They have capabilities in both biosimilar development and contract manufacturing for third parties.

ten23 health

Switzerland

Swiss CDMO specializing in formulation, analytical and process development, sterile manufacturing (fill and finish), and testing of injectable medicines. First CDMO in the pharmaceutical industry for injectables to be B Corp certified. Operates from Basel and Visp, Switzerland. Opened new VIVA2 facility with expanded sterile manufacturing lines. QC laboratories approved by both Swissmedic/RHI and FDA. Partners with BD on Libertas wearable injector commercialization. Supports biologics, small molecules, and RNA therapeutics.

Theon Pharmaceuticals Ltd.

India

Indian pharmaceutical contract manufacturer (third-party manufacturer) based in Baddi, Himachal Pradesh. WHO-GMP and ISO 9001:2008 certified. Specializes in manufacturing tablets, capsules, dry syrups, and injectables. Ranked among top 10 leading injectable companies. Launched new state-of-the-art injectable and ophthalmic formulations facility in October 2024 for regulated markets. Has multiple production sections: General, Beta Lactam, Cephalosporins, Dry Powder Injectable. Exports to Africa, South East Asia, CIS, Latin America, and Asia Pacific. Has 12 FDA-approved products including injectables and oral tablets.

Thermo Fisher Scientific Inc.

China

One of the world's largest pharmaceutical CDMOs through its Patheon pharma services division. Provides end-to-end pharmaceutical development and manufacturing services for both small molecules and biologics, from API manufacturing through drug product, sterile fill/finish, packaging, and commercial supply. Operates 31+ FDA-registered facilities globally. 158 FDA inspections on record (52 NAI, 104 VAI, 2 OAI). Also provides cell therapy manufacturing solutions (CTS Rotea cell processing system), laboratory informatics, bioprocessing equipment, and reagents. 4 FDA-approved drug products. Revenue >$40B (full company).

UI Pharmaceuticals

United States

UI Pharmaceuticals (UIP) is the largest and most experienced university-affiliated FDA-registered pharmaceutical manufacturing facility in the United States, operated by the University of Iowa. They offer comprehensive drug product CDMO services from formulation development through commercialization. In 2023, they launched a new 16,000 sq ft sterile processing facility with fill lines. They serve pharmaceutical, biotech, pediatrics, oncology, and research organizations worldwide.

Upperton Pharma Solutions

United Kingdom

Upperton Pharma Solutions is a UK-based CDMO with an award-winning 60,000 sq ft development and manufacturing facility (Trent Gateway) in Nottingham. They provide integrated services from pre-clinical through late-phase manufacture for oral solids, nasal, pulmonary, and parenteral dosage forms. They recently built a new 7 million GBP sterile fill/finish manufacturing facility with MHRA submission. Services include formulation development, clinical supply manufacturing (Phase I-III), process scale-up and optimization, quality control, and analytical development and validation.

Wacker Biotech

Germany

Wacker Biotech is the CDMO division of Wacker Chemie AG, specializing in advanced biologics manufacturing including proteins, plasmid DNA, mRNA, LNP formulations, live microbial products, and vaccines. With over 30 years of experience and five GMP-compliant facilities in Germany, the Netherlands, and the United States, Wacker Biotech offers process development through commercial-scale manufacturing with E. coli-based technology platforms.

Waisman Biomanufacturing

United States

Waisman Biomanufacturing is an academic CDMO based at the Waisman Center at the University of Wisconsin-Madison, specializing in advancing novel biologics and vaccines into early clinical trials. The facility manufactures plasmid DNA, recombinant proteins, cell therapeutics, extracellular vesicle/secretome products, live biotherapeutic products, and viral vectors under cGMP conditions.

WuXi Biologics

China

WuXi Biologics is a leading global Contract Research, Development, and Manufacturing Organization (CRDMO) for biologics, with over 12,000 employees across the US, Ireland, Germany, China, and Singapore. The company provides end-to-end solutions from discovery through commercial manufacturing for biologics including monoclonal antibodies, bispecifics, ADCs, vaccines, and mRNA products using both mammalian and microbial expression systems.

Xellia Pharmaceuticals

China

Xellia Pharmaceuticals is the global leader in fermentation-based non-beta-lactam anti-infective APIs and finished dosage forms (FDFs). With over 120 years of pharmaceutical manufacturing heritage, they supply APIs and sterile injectables to over 500 pharmaceutical companies across 80 countries. Also operates as a CMO for third-party sterile injectable production.

Xi'an Wanlong Pharmaceutical

China

Xi'an Wanlong Pharmaceutical Co., Ltd. is a comprehensive modern pharmaceutical enterprise founded in 1995, primarily producing formulations, APIs, and intermediates with GMP and DMF compliance. The Yangling facility spans 200,000 sq.m. with 18 production lines for injections, tablets, capsules, powder, and raw materials.

Zydus Lifesciences Ltd

India

Zydus Lifesciences Ltd. (formerly Cadila Healthcare) is a major Indian pharmaceutical company headquartered in Ahmedabad, Gujarat, ranked 4th in the Indian pharma industry with 29,000+ employees globally. In June 2025, Zydus entered the global biologics CDMO business by acquiring Agenus Inc.'s U.S. manufacturing facilities in Emeryville and Berkeley, California for $75M upfront (plus $50M milestones), now operating as independent subsidiary Zylidac Bio LLC. These facilities provide end-to-end biologics development and manufacturing from pre-clinical to commercial stages, including monoclonal antibody manufacturing for Phase-3 immuno-oncology products (Botensilimab and Balstilimab). Zydus has 15 FDA-registered facilities, 156 FDA-approved products across capsules, tablets, creams, gels, injectables (including liposomal), ointments, suppositories, and transdermal patches. They have 58 FDA inspections (25 NAI, 28 VAI, 5 OAI) and 51 recalls (2 Class I, 40 Class II, 9 Class III). Manufacturing sites span Gujarat, Maharashtra, Goa, Himachal Pradesh, Sikkim (India), plus US (Vermont, Pennsylvania, Missouri) and Brazil. Their CDMO services are specifically the biologics arm through Zylidac Bio -- the broader Zydus business is primarily own-brand generic pharmaceuticals.

Adragos Pharma

Germany

Adragos Pharma is a globally operating CDMO headquartered in Munich, Germany, specializing in small molecule finished dosage forms. They operate six manufacturing sites across Europe and Japan: Athens (Greece, HPAPI capabilities), Halden (Norway, BFS sterile production), Jura (Switzerland, small-batch clinical/commercial), Kawagoe (Japan, ampoules and tablets), Livron (France, sterile liquids and suppositories), and Leipzig (Germany, semi-solid and non-sterile liquids).

Afton Scientific

United States

Afton Scientific is a pharmaceutical CDMO with over 20 years of expertise in aseptic manufacturing for biologics and small molecules. The company operates FDA-inspected facilities with a 99.9% on-time delivery rate and is investing in multi-year expansion of sterile fill-finish capabilities, including new technologies for improved efficiency and increased production capacity.

Alcami

United States

Alcami is a US-based CDMO with 45+ years of experience providing integrated drug product manufacturing, laboratory services, and cGMP pharmaceutical storage. The company specializes in sterile fill-finish manufacturing (liquid and lyophilized injectables, prefilled syringes) and oral solid dose, with DEA licensing for controlled substances and EU/Annex 1 compliance.

Aldevron

United States

Aldevron is a US-based CDMO specializing in manufacturing plasmid DNA, mRNA, and related products for gene therapy, cell therapy, gene editing, and RNA vaccines/therapeutics. The company offers custom and catalog products from research grade through cGMP, with capabilities including mRNA production with LNP encapsulation and fill/finish, supporting discovery through commercialization.

American Injectables

United States

American Injectables is a privately held, FDA-approved CDMO specializing in sterile injectable drug products. Based in Florida, the company provides end-to-end services from formulation development through commercial manufacturing, with capabilities in aseptic fill/finish for vials and syringes, analytical testing, packaging, and serialization.

Argonaut Manufacturing Services

United States

Argonaut Manufacturing Services is a U.S.-based CMO headquartered in Carlsbad, California, specializing in aseptic fill and finish, lyophilization (LyoDose beads, LyoDots, powders, and cakes), in-vitro diagnostics (IVD) and life science kit manufacturing, and drug-device combination products (DDCP). They recently secured $45M in financing to expand their aseptic fill/finish capabilities. They serve pharmaceutical, life science, IVD, and applied markets from small N-of-1 fills to high-scale commercial products.

Astrea Pharma

France

Astrea Pharma is a CDMO founded with the purpose of building a customer-focused manufacturing network covering development to commercial supply. They acquired the Fontaine-les-Dijon solid dose manufacturing site from Recipharm and offer oral solid dose and aseptic manufacturing capabilities from development through commercial supply, with a focus on efficiency and value in the pharma supply chain.

August Bioservices

United States

August Bioservices is a US-based CDMO headquartered in Nashville, Tennessee, specializing in sterile injectable drug product development and manufacturing. They offer end-to-end services from lab-scale process development through commercial manufacturing, including formulation, analytical method development and validation, sterile filling for vials, syringes, and IV bags using both stainless steel and single-use technology (1L to 4000L), lyophilization, automated visual inspection, assembly, labeling, packaging, and serialization. The company operates fully isolated filling lines and drug-device combination product capabilities.

Avara Pharmaceutical Services

United States

Avara Pharmaceutical Services is an international contract manufacturing organization (CMO) headquartered in Norman, Oklahoma, specializing in commercial-scale drug product manufacturing. Their core capabilities include oral solid dose (including potent compounds and targeted release formulations) with capacity of 1.5 billion doses per year, liquid and lyophilized sterile injectable fill-finish with terminal sterilization and high containment, and integrated packaging with serialization, automated inspection, and specialty packaging. Avara operates former branded pharmaceutical facilities in the US (Norman, Oklahoma and Arecibo, Puerto Rico) and Italy (Liscate), serving 40+ countries. Facilities hold approvals from FDA, DEA, ANVISA, MPA (Sweden), and other international agencies.

BioCina

Australia

BioCina is a global end-to-end biologics CDMO and the only biologics CDMO in Australia approved by the US FDA. Following the merger with NovaCina, the company provides comprehensive biologics CDMO services spanning cell line development, process development, analytical development, GMP manufacturing of biologics drug substance and drug product, and mRNA manufacturing. Operates facilities in Adelaide, Australia with GMP manufacturing capacity up to 1,000L bioreactors.

BioConnection

Netherlands

BioConnection is a contract manufacturing organization (CMO) based in Oss, The Netherlands, specializing in aseptic fill and finish services for sterile drug products. The company offers flexible development and GMP-compliant manufacturing for both innovative and generic biopharmaceutical companies, with capabilities in vials, syringes, and lyophilized products. Partnered with AGC Biologics for drug product services. FDA-registered with 17 inspections (6 NAI, 11 VAI), demonstrating extensive regulatory history.

Birgi Mefar Group (BMG)

Turkey

Birgi Mefar Group (BMG) is one of Turkey's leading producers of sterile injectable products, recently acquired by Abu Dhabi-based ADQ. The company provides contract manufacturing services for sterile injectables with manufacturing sites in Turkey. BMG is listed on pharmaceutical CDMO directories and provides fill-finish and sterile manufacturing services.

Bliss GVS Pharma Ltd.

India

Bliss GVS Pharma Ltd. is an Indian pharmaceutical company and the world's largest manufacturer of suppositories and pessaries, operating in 60+ international markets. The company operates six manufacturing units in Maharashtra and Daman with WHO-GMP and EU-GMP (PIC/S) approvals, producing suppositories, pessaries, tablets, dry syrups, dry powder injectables, ointments, creams, and gels. Bliss GVS offers contract manufacturing (CMO/CDMO) services alongside its own product portfolio.

Bruschettini S.r.l.

Italy

Bruschettini S.r.l. is an Italian pharmaceutical company based in Genoa that provides contract manufacturing services for sterile injectable and lyophilized products. The company is listed on CMO/CRO directories and appears in contract pharmaceutical dose manufacturing industry reports as a provider of sterile manufacturing capabilities.

Cenexi

Belgium

Cenexi is a Belgian/French CDMO specializing in sterile products, biological and injectable pharmaceutical manufacturing. The company operates four manufacturing sites in Europe, including sites in Fontenay-sous-Bois and Herouville-Saint-Clair (France), Osny (France, for highly active solid pharmaceutical forms), and Belgium. Cenexi offers services from development to commercial production for pre-filled syringes, vials, lyophilized products, tablets, capsules, and syrups, with FDA-registered manufacturing operations.

Dalton Pharma Services

Canada

Dalton Pharma Services is a Canadian CDMO and subsidiary of Seikagaku Corporation Japan, providing integrated drug discovery, development, and manufacturing services. The company is FDA-inspected and Health Canada-approved with over 35 years of experience, specializing in custom chemical synthesis, cGMP API manufacturing, sterile vial filling, and formulation development including liposomal formulations. Dalton recently announced major expansion of its commercial sterile manufacturing capacity.

Danhson

Bulgaria

Danhson is a Bulgaria-based pharmaceutical holding company established in 2015, with group companies including Vetprom AD (65+ years of manufacturing history) and Danapha Pharmaceutical in Vietnam. The company develops, produces, and markets pharmaceutical products (Rx and OTC), food supplements, and cosmetics, with CMO/CDMO services. Danhson has invested BGN 50 million in a new production site with separate workshops for ampoule forms, liquid forms, semisolid, and biological products.

Delpharm

Canada

Delpharm is one of the world's top five CDMOs, specializing in the development and manufacture of medicines across solid, sterile, semi-solid, and liquid dosage forms with particular expertise in nasal sprays and injectables. The company operates 18 manufacturing sites and 3 development centers across Europe and North America, with 6,500 employees and over 1.1 billion EUR in turnover. Delpharm produces over 650 million units annually and recently received a $60 million Canadian government investment to modernize its Boucherville injectable facility.

Eckert & Ziegler

Germany

Eckert & Ziegler is a leading German specialist in isotope-related components for nuclear medicine and radiation therapy with over 1,000 employees. The company's Radiopharma division serves as a CMO for clinical and commercial supply of radiopharmaceuticals using alpha, beta, or gamma radiation, including Lutetium-177, Yttrium-90, Gallium-68, Actinium-225, and Thorium-227 products.

Eczacıbaşı-Monrol

Germany

Eczacibasi-Monrol (now acquired by Curium Pharma) is a global radiopharmaceutical company headquartered in Istanbul, Turkey, with 13 facilities across Eastern Europe, Middle East, and Africa regions. The company provides CDMO services for radiopharmaceutical development and manufacturing, including PET and SPECT products, and is one of the world's largest Lutetium-177 producers.

Enable Innovations S.r.l.

Italy

Enable Innovations is an Italian contract manufacturer specializing in the aseptic preparation and filling of sterile liquid products, particularly eye drops, nasal sprays, and inhalation solutions. Founded in 2009 in Carpi, Italy, the company operates fully automated production lines for medical devices, food supplements, and foods for special medical purposes.

Enzene Biosciences Limited

India

Enzene Biosciences is an Indian CDMO and subsidiary of Alkem Laboratories, specializing in biologics and biosimilar development and manufacturing. The company's patented EnzeneX continuous bioprocess manufacturing platform significantly reduces the cost of producing complex biologics and monoclonal antibodies, with facilities in Pune, India and an expanding site in Hopewell, New Jersey, USA.

EVER Pharma

Austria

EVER Pharma is an Austrian fully integrated specialty pharmaceutical company and CDMO with over 60 years of sterile production experience, specializing in complex injectables. The company operates a state-of-the-art GMP facility in Jena, Germany producing 400+ pharmaceutical products, with particular expertise in highly active substances (narcotics, hormones, cytotoxics), crystal suspensions, and oily solutions in vials, pre-filled syringes, cartridges, implants, and ampoules.

Exela Pharma Sciences

United States

Exela Pharma Sciences is a US-based integrated specialty pharmaceutical company and CDMO founded in 2005, specializing in sterile injectable development and manufacturing. The company operates FDA-inspected cGMP facilities in Lenoir, North Carolina, with capacity to produce over 100 million sterilized units annually across liquid vials, IV bags, lyophilized vials, and pre-filled syringes.

FinVector

Finland

FinVector is a Finnish cGMP manufacturer of viral-based gene therapy products with over 30 years of experience in drug discovery science and manufacturing. Its new 25,000 square meter Finport facility in Kuopio, opened in partnership with Ferring Pharmaceuticals, represents one of the world's largest viral vector manufacturing capacities using the iCELLis platform from Pall Corporation.