Metabolic Disease CDMOs

UPM Pharmaceuticals

United States

UPM Pharmaceuticals is a U.S.-based CDMO specializing in late-stage commercial manufacturing of semi-solid and oral solid dose products. Operating from a 475,000 sq ft cGMP FDA-registered facility in Bristol, Tennessee, UPM is a family-owned company with 30+ years of experience. They handle DEA-controlled substances and provide services from technology transfer and scale-up through commercial manufacturing. Capabilities include formulation development, analytical development, coated tablet manufacturing, pharmaceutical serialization, aggregation, and full packaging and warehousing.

Ami Lifesciences Pvt Ltd

India

Ami Lifesciences Pvt. Ltd. is one of India's fastest-growing API manufacturing companies, established in 2006 in Vadodara, Gujarat. The company manufactures 88+ APIs across multiple therapeutic areas with 69 DMFs filed globally, operating three manufacturing plants with 1,500 metric tons of production capacity and offering CDMO/custom synthesis services.

TAPI (Teva API)

Netherlands

TAPI (Teva Active Pharmaceutical Ingredients) is the API division of Teva Pharmaceutical Industries, positioned as the world's leading international supplier of APIs with 350+ products in their portfolio. They offer integrated API and CDMO services, leveraging 85+ years of API development and manufacturing expertise. TAPI provides customized solutions including complex API development, peptide manufacturing (including GLP-1 capability), and end-to-end manufacturing. They have a partnership with Antheia for biosynthetic pharmaceutical ingredients and with Sagimet Biosciences for resmetirom API. TAPI operates globally with multiple manufacturing sites.

Akums Drugs & Pharmaceuticals Ltd

India

Akums Drugs & Pharmaceuticals Ltd. is India's largest CDMO with 30% domestic market share, operating 15+ state-of-the-art manufacturing facilities with over 4,100 commercialized formulations across 60+ dosage forms. The company serves 1,500+ pharmaceutical companies and provides end-to-end services including API manufacturing (737 MT annual capacity across 3 facilities), formulation development, clinical trial materials, and commercial-scale production of tablets, capsules, injectables, soft gels, syrups, topicals, and nutraceuticals.

Biomatrix Healthcare Pvt. Ltd.

India

BioMatrix Healthcare Pvt. Ltd. is an Indian pharmaceutical company established in 2007, headquartered in Ahmedabad, specializing in 100% export of pharmaceutical products to 40+ countries. Their manufacturing facility is WHO-GMP, EU-GMP certified and compliant with US-FDA, UK-MHRA, and ANVISA standards, with Health Canada site approval. Capacity: 5 billion tablets, 1 billion capsules, 24 million liquids, and 18 million dry syrups per annum. 1,000+ product registrations. Expanding with a new API manufacturing facility in Vadodara.

West Bengal Chemical Industries Limited

India

West Bengal Chemical Industries Limited (WBCIL) is a GMP and ISO certified API manufacturer based in Kolkata, India, with over 60 years of experience. The company specializes in producing active pharmaceutical ingredients including injectable iron APIs, chelated minerals, and liposomal technology products. WBCIL holds multiple FDA registrations across four FEI numbers.

AmbioPharm

China

AmbioPharm is a global peptide CDMO founded in 2005 and headquartered in North Augusta, South Carolina, USA. The company specializes in developing and manufacturing custom peptide APIs for pharmaceutical and biotech companies, with FDA-inspected facilities in the US and China and one of the largest peptide manufacturing capacities in the world.

Shenzhen Hybio Pharmaceutical Co., Ltd. (Hybio) is a Chinese pharmaceutical company founded in 1998, specializing in peptide drug R&D, manufacturing, and commercialization with a CRDMO division. The company focuses on peptide APIs (including semaglutide) and sterile injectable formulations, with products sold in 30+ countries. Hybio has 7 FDA-registered facilities and a strategic partnership with Dr. Reddy's for peptide API supply, and recently partnered with Huawei for AI-driven drug development.

Yungjin Pharm. Co., Ltd. is a South Korean domestic pharmaceutical company established in 1952, operating as an affiliate of the KT&G group. The company manufactures and sells its own pharmaceutical products including cephalosporin finished products. Website content was inaccessible (frame-based site). No evidence of contract manufacturing services.

Asymchem

China

Asymchem is a leading CDMO with 25+ years of experience, 9,700+ employees, and eight R&D and manufacturing sites. They specialize in complex chemistry for small molecule APIs, including peptide synthesis, and provide comprehensive CMC services from R&D through commercial production. They have 65+ successful regulatory inspections (FDA, NMPA, TGA, MFDS) and 1,100+ active clients with 600+ clinical and 40+ commercial projects.

Akriti Pharmaceuticals Pvt. Ltd.

India

Akriti Pharmaceuticals Pvt. Ltd. is an Indian pharmaceutical manufacturer with EU GMP and TGA approved manufacturing facilities. The company delivers affordable quality medicines across the world with efficient manufacturing services backed by a qualified technical team, operating as a contract manufacturer for global healthcare partners.

AB Biotechnology Ltd

United Kingdom

AB Biotechnology Ltd is a UK-based biologics CDMO located at Pentlands Science Park near Edinburgh. They specialize in development and GMP manufacturing of high-purity biopharmaceutical products including proteins, peptides, and polyclonal antibodies. Their MHRA-licensed facility includes cleanroom suites for purification, viral inactivation/reduction, fill/finish, and lyophilization for injectables.

Baxter International

China

Baxter International is a global medtech and biopharma company. Through its BioPharma Solutions (BPS) division, Baxter operates as a major CDMO providing sterile fill/finish manufacturing services. BPS invested over $150M in expanding sterile fill/finish capacity at its Bloomington, Indiana facility. Note: Baxter has signed a definitive agreement to divest its BioPharma Solutions business. Baxter has 308 FDA-approved products, extensive manufacturing facilities worldwide, and 93 FDA inspections on record.

Iasis Pharma S.A.

Greece

Iasis Pharma S.A. is a steadily growing Greek pharmaceutical company founded in Athens, engaged in the manufacture and marketing of a wide range of pharmaceutical products across multiple therapeutic areas. The company operates production facilities and offers products including oral solids, injectables, and topicals.

Bachem AG

Switzerland

Bachem AG is a leading global CDMO specializing in the development and manufacture of peptides and oligonucleotides, with over 50 years of experience. Headquartered in Bubendorf, Switzerland, Bachem provides end-to-end services from research-grade synthesis and CMC development through GMP-scale commercial API manufacturing for pharmaceutical and biotechnology companies worldwide. The company leverages innovative technologies including Multi-Column Solvent Gradient Purification (MCSGP) for higher throughput and purity. Bachem holds a strong regulatory track record and a partnership with Eli Lilly for oligonucleotide-based drug substance development and manufacturing (since April 2022). They serve the peptide therapeutics market including GLP-1 receptor agonists and other complex peptide APIs.

Aizant Drug Research Solutions

India

Aizant Drug Research Solutions Pvt. Ltd., founded in 2008, is a trusted global CDMO offering comprehensive API and Formulation R&D, CDMO, CMO, and CRO services across multiple therapeutic areas and dosage forms. The company operates USFDA and EU-accredited facilities with capabilities in hot melt extrusion, spray drying, and complex generics, providing end-to-end pharmaceutical development and manufacturing solutions.

Suzhou Lixin Pharmaceutical Co., Ltd. is a privately-owned Chinese GMP manufacturer specializing in Active Pharmaceutical Ingredients (APIs) and intermediates, established in 2000. The company produces APIs including semaglutide, sitagliptin phosphate, and indapamide, with multiple FDA-registered facilities that have been FDA-inspected.

Sekisui XenoTech LLC

United States

Sekisui XenoTech LLC is a US-based specialty Contract Research Organisation (CRO) providing comprehensive drug metabolism and drug-drug interaction (DDI) studies. Now operating as XenoTech, a BioIVT company following acquisition, the company provides ADME testing services, cell culture products, and preclinical testing services for drug development. It is not a drug manufacturer.

Hanmi Pharm. Co. Ltd

South Korea

Hanmi Pharmaceutical is a major South Korean pharmaceutical company providing comprehensive CDMO services across the entire pharmaceutical lifecycle. The company operates through Paltan Smart Plant (producing 6+ billion chemical drug tablets annually), Pyeongtaek Bioplant (FDA-approved biopharmaceutical manufacturing with 12,500L bioreactors), and Hanmi Fine Chemical (API and raw materials including mRNA cap analogs, NTP, and lipids). Hanmi has partnerships with global pharma companies including Lilly, Roche, and Sanofi.

Ultratech India Limited

India

Ultratech India Limited is an integrated Indian pharmaceutical company established in 1992, manufacturing pharmaceutical finished dosage forms, Active Pharmaceutical Ingredients, and drug intermediates. They specialize in pulmonary drug delivery systems (DPI and pMDI inhalation products) and offer Custom Research and Manufacturing Services (CRAMS) including custom synthesis, process development, private labeling, and contract manufacturing. Extensive API portfolio covers cardiovascular, antifungal, antihistamine, anti-asthmatics, antiviral, erectile dysfunction, and other therapeutic segments. WHO GMP, ISO 9001, ISO 14001 certified.

ICROM S.p.A.

Italy

ICROM S.p.A. is an Italian custom API development and manufacturing company based in Concorezzo (MB), specializing in custom development, custom manufacturing, and APIs for specialty drugs. The company operates under cGMP with inspections by AIFA, USFDA, PMDA, and KFDA, and holds Drug Master Files in all major regulatory markets. ICROM recently acquired Holodiag and has a subsidiary Proxis.

Acino International AG

Switzerland

Acino International AG is a Swiss pharmaceutical company headquartered in Zurich, operating as a CDMO specializing in oral solid dosage forms. With over 50 years of manufacturing experience, they operate facilities in five countries with annual capacity of billions of tablets and millions of capsules. They specialize in advanced drug delivery systems including multi-unit pellet systems (MUPS), minitablets, and complex modified-release formulations.

TITAN PHARMAPLUS PVT. LTD

India

Titan Pharmaplus Pvt. Ltd. is an Indian pharmaceutical API manufacturer and CDMO committed to innovation, quality, and sustainability. The company produces a wide range of small molecule APIs including Apixaban, Dapagliflozin, Acyclovir, Dexlansoprazole, and controlled substances, with state-of-the-art cGMP facilities and advanced chemical synthesis capabilities including high-pressure hydrogenation, Grignard reactions, and asymmetric oxidation.

AbbVie Contract Manufacturing (AbbVie CMO)

Italy

AbbVie Contract Manufacturing is an embedded CMO within AbbVie, providing third-party contract manufacturing services for over 40 years across 12 locations in the US and Europe. They offer services spanning antibody drug conjugates, aseptic fill/finish, biologics (mAbs and derivatives), custom API, eye care, hot melt extrusion, HPAPI, and oral solid dose manufacturing.

Vistin Pharma AS

Norway

Vistin Pharma AS is a Norwegian pharmaceutical company dedicated to the production of Metformin Hydrochloride API and direct compression grade. Operating a state-of-the-art manufacturing plant, the company is undergoing a capacity expansion to >7,000 MT/year (doubling current capacity). FDA registered (FEI 3006272184) with 4 inspections (all VAI, latest January 2025). ISO 14001 certified. Vistin is a dedicated single-product API manufacturer, not a CDMO -- it manufactures its own product line of Metformin HCl.

Fresenius Kabi iPSUM S.r.l.

Italy

Fresenius Kabi iPSUM S.r.l. is the Italian subsidiary of Fresenius Kabi, a global healthcare company with significant CDMO operations specializing in lifesaving medicines for critically and chronically ill patients. The company has extensive FDA-registered manufacturing facilities with 405 FDA-approved products, and provides contract development and manufacturing services for injectable, infusion, and other sterile pharmaceutical products.

BioInnovatise, Inc.

United States

BioInnovatise is a US-based CDMO specializing in quick-turnaround molecular biology services for early-stage drug discovery. Services include plasmid DNA services, viral vector packaging, and CRISPR-Cas9 services. The company collaborates with researchers in government, academia, and industry, focusing on custom cloning and the early discovery phase of drug development.

Ethypharm

China

Ethypharm is a leading mid-size international specialty pharmaceutical company and CDMO with 5 manufacturing plants across France, UK, and Spain. The company specializes in oral solid dosage forms, sterile injectables in ampoules, pre-filled syringes and IV bags, with particular expertise in high potent APIs and controlled substances including opioids and psychotropics.

Novartis Contract Manufacturing

Austria

Novartis Contract Manufacturing is the CDMO arm of Novartis, offering fully integrated end-to-end manufacturing solutions across biologics (mammalian up to 15,000L, microbial up to 13,000L), small molecules (API to fill & finish), cell & gene therapy (CAR-T, AAV, LV), xRNA/LNP/pDNA, and comprehensive fill & finish services. The operation spans multiple state-of-the-art facilities across Austria, Switzerland, Slovenia, Belgium, France, Singapore, and the United States, with 107 FDA inspections and 27 FEI registrations.

Addii Biotech Pvt Ltd

India

Addii Biotech Pvt Ltd is an Indian pharmaceutical company established in 2010, initially as a marketing company that expanded into manufacturing in 2017. They manufacture tablets, capsules, ointments, dry syrups, and other preparations at their WHO-GMP certified facility in Baddi, Himachal Pradesh. They hold ISO 9001:2015, WHO-GMP, and FDA-Ghana certifications and supply to government institutions and hospitals.

Catalent Pharma Solution

Argentina

Catalent is a leading global CDMO trusted by pharma, biotech, and self-care companies to accelerate the development, manufacturing, and delivery of products that improve lives. With a worldwide network of facilities, advanced technologies, and deep expertise, Catalent provides integrated end-to-end solutions spanning oral dose, biologics, specialty therapies, cell and gene therapy, and clinical supply. The company partners with innovators from early-stage design through commercial manufacturing.

Parexel International (MA) Corporation

Argentina

Parexel is a global contract research organization (CRO) providing clinical trial management, regulatory consulting, and biopharmaceutical development services. With over 24,000 professionals and 50+ clinical sites across five continents, the company offers Phase I-IV clinical trial services, CMC regulatory strategy, and real-world evidence generation. Parexel is primarily a CRO, not a drug manufacturer.

Apotex (incl. Apotex Pharmachem)

Canada

Apotex is Canada's largest pharmaceutical company with global operations spanning API manufacturing, finished dosage form production, and CDMO/co-development services. With capacity to produce approximately 25 billion finished doses annually and three API manufacturing sites, they serve both their own generic portfolio and external partners through Apotex Pharmachem (API CDMO) and Apotex Fermentation (fermentation-based manufacturing).

Jiangsu Hengrui Medicine Co., Ltd. is China's largest listed pharmaceutical company, founded in 1970, with over 20,000 employees globally. Hengrui is primarily an innovation-driven pharma company developing and manufacturing its own drugs across oncology, cardiovascular, metabolism, autoimmune, pain, and anti-infection therapeutic areas, with a pipeline of 257 drugs and 24 Class 1 innovative drugs. While it has some CDMO references in search results, Perplexity research confirms it primarily specializes in proprietary drug development and manufacturing rather than contract services.

Changzhou Comwin Fine Chemicals Co., Ltd

China

Changzhou ComWin Fine Chemicals Co., Ltd., a subsidiary of ComWin International established in 2003, specializes in producing and distributing APIs, animal healthcare products, and nutritional ingredients. The company operates a 70,000 sqm manufacturing site in Taizhou, China, and provides international logistics services including cold-chain and hazardous shipment to clients such as Sanofi and Vetoquinol.

Galenicum Health

Spain

Galenicum Health is a Spanish specialty pharmaceutical company founded in 2003 in Barcelona, operating as a CDMO with a manufacturing facility near Madrid. The company produces finished dosage forms in multiple formats including liquids, ointments, creams, sachets, powders, nasal sprays, tablets, and capsules, with a production capacity of over 50 million packs per year. Galenicum operates in 58+ countries with 800+ employees and consolidated revenues of 213M EUR (2023).

Sun Pharmaceutical Industries Ltd. (Sun Pharma) is one of the world's largest specialty generic pharmaceutical companies, headquartered in Mumbai, India. While the company has massive manufacturing operations (1,075 FDA-approved products, 25+ FDA-registered FEI numbers), it primarily manufactures and markets its own branded and generic pharmaceutical products rather than providing contract manufacturing services to third parties as a CDMO.

HEC (HEC Pharm / Sunshine Lake Pharma)

China

HEC Pharm (also known as Sunshine Lake Pharma or Guangdong HEC Pharma) is a Chinese integrated pharmaceutical company established in 2003, focused on drug R&D, production, and commercialization of innovative drugs, generics, and biosimilars. The company specializes in anti-infection (oseltamivir) and chronic disease therapeutic areas with over 6,000 employees and 100+ R&D projects.

AMN Life Science Pvt Ltd

India

AMN Life Science Pvt Ltd is an Indian pharmaceutical company headquartered in Mumbai, engaged in pharmaceutical product development and manufacturing of formulations for international markets. The company manufactures a range of oral solid dosage and oral liquid products across therapeutic areas including gastrointestinal, antibiotics, and nutraceuticals, with EU GMP and WHO cGMP certifications.

AnaSpec, Inc.

United States

AnaSpec, Inc., a Kaneka Corporation subsidiary, is a globally recognized biotechnology company delivering R&D, GLP, and GMP-grade peptide and dye products and services. The company manufactures custom GMP peptides for diagnostic testing, biopharmaceutical manufacturing, and other applications, with FDA-registered API manufacturing operations and cleanroom manufacturing facilities.

Aurigene Services

India

Aurigene Pharmaceutical Services (formerly Aurigene Services) is a leading global CRDMO with 25+ years of experience, offering integrated CRO (discovery) and CDMO services for both small and large molecules. The company provides end-to-end drug development solutions from target identification through commercial manufacturing, operating 16 USFDA-approved sites. Aurigene has 700+ scientists, 400+ completed projects, and 18 successfully commercialized NCEs. Their small molecule CDMO capabilities span drug substance development and manufacturing, formulations, and specialty areas including peptides, high potent APIs, mPEGs, steroids, carbohydrates, and flow chemistry. Their biologics division offers process development and clinical scale manufacturing for monoclonal antibodies, bispecific antibodies, and proteins, with a new biomanufacturing facility in Hyderabad.

Theon Pharmaceuticals Ltd.

India

Indian pharmaceutical contract manufacturer (third-party manufacturer) based in Baddi, Himachal Pradesh. WHO-GMP and ISO 9001:2008 certified. Specializes in manufacturing tablets, capsules, dry syrups, and injectables. Ranked among top 10 leading injectable companies. Launched new state-of-the-art injectable and ophthalmic formulations facility in October 2024 for regulated markets. Has multiple production sections: General, Beta Lactam, Cephalosporins, Dry Powder Injectable. Exports to Africa, South East Asia, CIS, Latin America, and Asia Pacific. Has 12 FDA-approved products including injectables and oral tablets.

IOL Chemicals & Pharmaceuticals Ltd.

India

IOL Chemicals & Pharmaceuticals Ltd is one of the world's largest manufacturers of Ibuprofen API and a leading producer of specialty chemicals including Ethyl Acetate. The company operates a fully backward-integrated, single-location manufacturing campus spanning 150+ acres in Barnala, Punjab, India, with 10 dedicated production units including USFDA-audited and EU-GMP approved facilities. Key APIs include Ibuprofen, Paracetamol, Clopidogrel Bisulphate, Pantoprazole Sodium, and Metformin HCL.

Hefei Home Sunshine Pharmaceutical Technology Co., Ltd.

China

Hefei Home Sunshine Pharmaceutical Technology Co., Ltd., founded in 2013 in Hefei City, China, is an ISO 9001:2015 certified manufacturer and supplier of Active Pharmaceutical Ingredients, intermediates, and fine chemicals. The company specializes in APIs for diabetes, oncology, and CNS therapeutic areas, as well as specialized resin products for peptide API production.

Corning Incorporated (Life Sciences & Pharmaceutical Technologies)

India

Corning Incorporated's Pharmaceutical Technologies division manufactures advanced glass packaging solutions for the pharmaceutical industry, most notably Valor Glass vials and containers designed for drug storage and delivery. The company is a materials science and glass technology company, not a drug manufacturer or CDMO.

IDI Integratori Dietetici Italiani srl is an Italian pharmaceutical company engaged in the development and manufacturing of pharmaceutical products, dietary supplements, and medical devices. The company has FDA-registered facilities and produces a range of products including tablets, creams, oral solutions, and injectable formulations across multiple therapeutic areas.

Egis Pharmaceuticals PLC

Hungary

Egis Pharmaceuticals PLC is a Hungarian generic pharmaceutical company with over 110 years of history, now offering CDMO services through its Egis Pharma Services division. The company operates three production sites in Hungary (two in Budapest, one in Kormend) and manufactures APIs, tablets, injections, and galenic formulations including ointments, suppositories, and syrups. Egis specializes in highly potent API development and manufacturing using organic chemical synthesis on GMP-compliant multi-functional lines for oncology and rheumatic arthritis therapies.

IBSA Institut Biochimique SA

Italy

IBSA (Institut Biochimique SA) is a Swiss multinational pharmaceutical company founded in 1945 in Lugano, with products present in over 90 countries. The company develops and manufactures innovative pharmaceutical products across 10 therapeutic areas with proprietary drug delivery technologies, including oral films, patches, and gonadotropin purification processes. IBSA has FDA-approved products in multiple dosage forms.

Hubei Hongyuan Pharmaceutical Technology Co., Ltd.

China

Hubei Hongyuan Pharmaceutical Technology Co., Ltd. (branded as HY Pharma / Zhejiang Hongyuan Pharmaceutical) is a Chinese pharmaceutical company established in 2005, now a subsidiary of the Wuchan Zhongda Group (Fortune 500). The company focuses on cardiovascular and hypoglycemic drug substance, API, and finished dosage form development and manufacturing, with 21+ invention patents.

ACON Pharmaceuticals

United States

ACON Pharmaceuticals Inc is a specialty contract research organization (CRO) based in Cranbury, New Jersey, focused on drug product development. They specialize in drug delivery systems including siRNA, mRNA, liposomes, nanocrystals, and complex generics development via the 505(b)(2) pathway. They are primarily a development-focused CRO, not a manufacturing organization.